https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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2009, discovery of a new phenotype for germs in slim nanofluidic slits; and 1st detection of community protein buildings together DNA working with good-point out nanopores
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Back again in 1991, Sumio Iijima with the NEC Company experienced described the synthesis of carbon nanotubes. Band framework calculations recommended that these nanotubes could exhibit metallic band conduction. This could be a substantial advantage more than the conducting polymers we had explored, which were, actually, disordered semiconductors providing merely variable-variety hopping conductivity.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. Inside of only some months, we have been able to evaluate transportation via somebody single-walled carbon nanotube. Based upon minimal-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with an Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Our investigation ranges through the biophysics of DNA to synthetic cells and past. Make sure you have a look below in the spectrum of our present projects.
All parameters ended up https://www.ceesdekker.net a similar for each panel Within this video clip, apart from the First placement on the 6hb rod (revealed in blue) over the nanopore. Simulations that terminated early because of translocation in the rod with the pore are marked by a gray track record.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
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It had been through this era that Dekker carried out study on magnetic spin techniques and on sound in superconductors and semiconductors.
Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
Nature Physics many thanks the anonymous reviewers for their contribution to your peer assessment of this operate.
For example, we think about the nucleopore advanced, a gateway amongst the cell nucleus and the cytoplasm. This is a really challenging program and therefore tricky to review within a mobile, so we use biomimetics. We reconstruct holes and afterwards insert specific components of your nucleopore intricate to study transportation by means of it at The one-molecule stage.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)